Do you have hard to control blood pressure and have not had success finding the right drug?  Do you have anxiety and are scared to try new medications?  Are you confident your child needs medication to help them focus but do not want to waste time finding the right medication?

If so, you are not alone.  Most people would prefer to find the right medication at the first time.  With experience a good family doctor can get it right on average by the second time.

We have been studying the research for pharmacogenomics for over 10 years and have not been ready to introduce it to our patients until now.

We are confident that there is enough research out there that can properly point us in a direction that shows which enzymes work best with the respective medication.  This research is called pharmacogenomics and is only getting better over time.

We have just started offering this to our patients and we will be able to help them understand which medications will work best on their body.

The test is a blood test and it will stay in a database that can be used in the future as more data is obtained on each drug and genome.

What this means is we can tell you which statin drug would have the best probability of working in your body and which ones are more likely to cause side effects.

If you are interested, please ask your PrimeCare physician about this test.  Not all insurances will pay for this testing, however, the cost may be just the same as multiple visits to get a specific medication that works for you.

The list of drugs we can test will grow over time and the information will continue to help us be more exact.  The following pharmacogenomics panels will be available for you at our Novi office:

Antiplatelet Agents – Aspirin, Cilostazol, Clopidogrel, Prasugrel, Ticagrelor

Statins -Atorvastatin, Fluvastatin, Lovastatin,Pitavastatin,Pravastatin, Rosuvastatin, Simvastatin

Anticlotting Agents – Acenocoumarol,Coumarol,Fluindione,Phenprocoumon, Warfarin

Thrombophilia – Susceptibility to Factor II, Factor V Leiden

Calcium Channel Blockers – Amlodipine, Nifedipine

Beta Blockers – Bufuralol,Carvedilol,Metoprolol,Propranalol,Talinolol,Timolol

Congestive Heart Failure – Digoxin

Antiarrhythmics – Flecainide, Propafenone

Antihypertensives – Benazepril, Debrisoquine, Enalapril, Irbesartan, Losartan,

Olmesartan, Verapamil

Addiction to Alcohol, Cocaine, Heroin, Opioids, Tobacco – Bupropion, Disulfiram, Levodopa,Methadone,Naloxone,Naltrexone, Nicotine

ADHD-Atomoxetine, Dextroamphetamine, Methylphenidate

Alzheimer’s Disease – Donepezil, Galantamine, Olanzapine, Risperidone

Anxiety, Insomnia, Severe Agitation-Dexmedetomidine, Escitalopram, Lorazepam, Midazolam, Oxazepam, Venlafaxine

Autism Spectrum Disorders – Quetiapine, Risperidone

Bipolar Disorder – Lithium, Olanzapine, Quetiapine

Depressive Disorder and Major Depressive Disorder-Agomelatine,Amitriptyline, Antipsychotics (gen), Citalopram, Clomipramine, Desipramine, Diazepam, Doxepin,  Escitalopram, Fluoexitine, Fluvoxamine, Imipramine, Maprotiline, Milnacipran, Mirtazapine, Nortriptyline, Olanzapine,Opipramol, Paroxetine,Quetiapine, Sertraline, SSRIs (gen),Trimipramine, Venlafaxine, Vortioxetine

Epilepsy -Antiepileptics (gen),Carbamazepine,Clobazam, Lamotrigine, Mephenytoin, Phenobarbital, Phenytoin, Valproic acid

Parkinson’s Disease – Entacaptone

Schizophrenia – Antipsychotics (gen), Aripiprazole, Chlorpromazine, Clozapine, Fluphenazine, Haloperidol, Iloperidone, Nemonapride, Olanzapine, Quetiapine, Risperidone, Thioridazine, Trifluoperazine, Zuclopenthixol

Transplantation – Busulfan, Cyclophosphamide, Cyclosporine, Everolimus, Methylprednisone, Prednisone/Prednisolone, Sirolimus, Tacrolimus

Rheumatoid Arthritis – Leflunomide, Methotrexate, Sulfasalazine

Type-II Diabetes – Repaglinide, Sulfoureas (gen), Urea Derivatives (gen)

Gastritis and Colitis – Esomeprazole, Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole, Tacrolimus

Inflammation – Celecoxib, Dexamethasone, Diclofenac, Flurbiprofen, Lornoxicam, Prednisone/Prednisolone

Systemic Lupus Erythematosus-Cyclophosphamide

Gout – Allopurinol

Antihistamines – Fexofenadine

Antiasthmatics – Zafirlukast

HIV/AIDS-Atazanavir, Efavirenz, Etravirine, Indinavir, Lamivudine, Lopinavir,Nelfinavir, Nevirapine, Ritonavir, Zidovudine

Antifungals and Antibiotics – Daptomycin, Dicloxacillin, Erythromycin, Rifampicin, Sulfonamides (gen), Voriconazole

Pain Management – General – Alfentanil, Codeine, Fentanyl, Hydrocodone, Ketamine, Methadone, Morphine,Opioids (gen), Oxycodone,Sumatriptan,Tramadol

Sedatives and Relaxants, including muscle relaxants – Carisoprodol, Midazolam, Propofol, Rocuronium, Tolperisone

Alkaloids – Vincristine

Alkylating Agents-Cyclophosphamide, Dacacarbazine

Antimetabolites – Cytarabine, Fludarabine, Mercaptopurine, Methotrexate, Silibinin

Anthracyclines-Anthracyclines (gen), Doxorubicin, Epirubicin, Idarubicin

Kinase Inhibitors – Gefitinib, Icotinib, Imatinib, Sorafenib, Sunitinib

Platinum Derivatives -Carboplatin,Cisplatin,Oxaliplatin,Platinum Compounds (gen)

Steroid Hormone Inhibitors – Mitotane, Tamoxifen,Taxanes – Docetaxel, Paclitaxel, Taxanes (gen)

Topoisomerase Inhibitors – Etoposide, Irinotecan

Uracil Derivatives – Capecitabine, Fluorouracil, Folfox, Folox, Leucovorin, Tegafur, Xelox

Antiemetics – Dolasetron,Granisetron,Ondansetron

Anesthesiology – Nitrous Oxide

Beta Thalassemia – Deferasirox

Narcolepsy – Modafinil

Contraception – Oral Contraceptives (gen)

Erectile Dysfunction – Vardenafil

Bladder Control – Tolterodine